Monday 27 December 2010

Dimidril




Dimidril may be available in the countries listed below.


Ingredient matches for Dimidril



Diphenhydramine

Diphenhydramine hydrochloride (a derivative of Diphenhydramine) is reported as an ingredient of Dimidril in the following countries:


  • Bosnia & Herzegowina

  • Croatia (Hrvatska)

International Drug Name Search

Saturday 18 December 2010

Estalex




Estalex may be available in the countries listed below.


Ingredient matches for Estalex



Eperisone

Eperisone hydrochloride (a derivative of Eperisone) is reported as an ingredient of Estalex in the following countries:


  • Indonesia

International Drug Name Search

Vitulpas




Vitulpas may be available in the countries listed below.


Ingredient matches for Vitulpas



Hydrocortisone

Hydrocortisone 21-acetate (a derivative of Hydrocortisone) is reported as an ingredient of Vitulpas in the following countries:


  • Chile

International Drug Name Search

Thursday 16 December 2010

Carvedilol Arafarma Group




Carvedilol Arafarma Group may be available in the countries listed below.


Ingredient matches for Carvedilol Arafarma Group



Carvedilol

Carvedilol is reported as an ingredient of Carvedilol Arafarma Group in the following countries:


  • Spain

International Drug Name Search

Wednesday 15 December 2010

Ursotamin




Ursotamin may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Ursotamin



Ketamine

Ketamine hydrochloride (a derivative of Ketamine) is reported as an ingredient of Ursotamin in the following countries:


  • Germany

International Drug Name Search

Riluzole


Pronunciation: RIL-ue-zole
Generic Name: Riluzole
Brand Name: Rilutek


Riluzole is used for:

Treating patients with amyotrophic lateral sclerosis (ALS, Lou Gehrig disease) to prolong survival and/or to delay the need for surgery to help breathing (tracheostomy). It may also be used for other conditions as determined by your doctor.


Riluzole is a benzothiazole. Exactly how Riluzole works is not known. It may prevent further damage to certain brain cells (motor neurons) responsible for controlling muscle function.


Do NOT use Riluzole if:


  • you are allergic to any ingredient in Riluzole

Contact your doctor or health care provider right away if any of these apply to you.



Before using Riluzole:


Some medical conditions may interact with Riluzole. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of liver or kidney disease, abnormal liver function tests, or a low white blood cell count

Some MEDICINES MAY INTERACT with Riluzole. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Omeprazole or rifampin because the effectiveness of Riluzole may be decreased

  • Amitriptyline, phenacetin, quinolones (eg, levofloxacin), tacrine, or theophylline because actions and side effects of Riluzole may be increased

  • Medicines that may harm the liver (eg, acetaminophen, allopurinol, certain medicines for HIV infection, isoniazid, ketoconazole, methotrexate, methyldopa, sulfasalazine) because the risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver

This may not be a complete list of all interactions that may occur. Ask your health care provider if Riluzole may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Riluzole:


Use Riluzole as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Riluzole by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

  • Riluzole works best if taken on a regular basis.

  • Take Riluzole at the same time every day.

  • If you miss a dose of Riluzole, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Riluzole.



Important safety information:


  • Riluzole may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Riluzole. Using Riluzole alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Avoid drinking excessive amounts of alcohol while taking Riluzole to reduce the risk of liver damage.

  • Caffeine may increase the actions or side effects of Riluzole. Avoid large amounts of caffeine-containing foods and beverages, such as coffee, tea, cocoa, cola drinks, and chocolate.

  • Cigarette smoke or charcoal-broiled food may decrease the effectiveness of Riluzole. Contact your doctor with any questions or concerns.

  • Patients of Japanese descent and women may be at higher risk of developing side effects from Riluzole.

  • LAB TESTS, including liver function tests, may be required to monitor progress or to check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Riluzole with caution in ELDERLY patients with liver problems; they may be more sensitive to its effects.

  • Use Riluzole with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Riluzole while you are pregnant. It is not known if Riluzole is found in breast milk. Do not breast-feed while taking Riluzole.


Possible side effects of Riluzole:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Abnormal skin sensations around the mouth; diarrhea; dizziness; drowsiness; headache; loss of appetite; muscle weakness; nausea; stomach pain; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); cough, shortness of breath, or trouble breathing; fast or irregular heartbeat; frequent or painful urination; signs of infection (eg, fever, chills, sore throat); swelling of the hands or feet; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Riluzole side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Riluzole:

Store Riluzole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Riluzole out of the reach of children and away from pets.


General information:


  • If you have any questions about Riluzole, please talk with your doctor, pharmacist, or other health care provider.

  • Riluzole is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Riluzole. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Riluzole resources


  • Riluzole Side Effects (in more detail)
  • Riluzole Use in Pregnancy & Breastfeeding
  • Riluzole Drug Interactions
  • Riluzole Support Group
  • 1 Review for Riluzole - Add your own review/rating


  • Riluzole Monograph (AHFS DI)

  • Riluzole Professional Patient Advice (Wolters Kluwer)

  • riluzole Concise Consumer Information (Cerner Multum)

  • riluzole Advanced Consumer (Micromedex) - Includes Dosage Information

  • Rilutek Prescribing Information (FDA)



Compare Riluzole with other medications


  • Amyotrophic Lateral Sclerosis
  • Obsessive Compulsive Disorder

Monday 13 December 2010

Farma 12




Farma 12 may be available in the countries listed below.


Ingredient matches for Farma 12



Benzalkonium Chloride

Benzalkonium chloride (a derivative of Benzalkonium) is reported as an ingredient of Farma 12 in the following countries:


  • Colombia

International Drug Name Search

Sunday 12 December 2010

Vodelax




Vodelax may be available in the countries listed below.


Ingredient matches for Vodelax



Citalopram

Citalopram hydrobromide (a derivative of Citalopram) is reported as an ingredient of Vodelax in the following countries:


  • Turkey

International Drug Name Search

Naratriptan Hydrochloride




Naratriptan Hydrochloride may be available in the countries listed below.


Ingredient matches for Naratriptan Hydrochloride



Naratriptan

Naratriptan Hydrochloride (BANM, USAN) is known as Naratriptan in the US.

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Clorfeniramin




Clorfeniramin may be available in the countries listed below.


Ingredient matches for Clorfeniramin



Chlorphenamine

Chlorphenamine maleate (a derivative of Chlorphenamine) is reported as an ingredient of Clorfeniramin in the following countries:


  • Romania

International Drug Name Search

Thursday 9 December 2010

Myconormin




Myconormin may be available in the countries listed below.


Ingredient matches for Myconormin



Terbinafine

Terbinafine hydrochloride (a derivative of Terbinafine) is reported as an ingredient of Myconormin in the following countries:


  • Austria

  • Germany

  • Luxembourg

  • Switzerland

International Drug Name Search

Saturday 4 December 2010

Noscab




Noscab may be available in the countries listed below.


Ingredient matches for Noscab



Permethrin

Permethrin is reported as an ingredient of Noscab in the following countries:


  • Bangladesh

International Drug Name Search

Calcium Mylan




Calcium Mylan may be available in the countries listed below.


Ingredient matches for Calcium Mylan



Calcium Carbonate

Calcium Carbonate is reported as an ingredient of Calcium Mylan in the following countries:


  • France

International Drug Name Search

Tuesday 30 November 2010

Acido deidrocolico




Acido deidrocolico may be available in the countries listed below.


Ingredient matches for Acido deidrocolico



Dehydrocholic Acid

Acido deidrocolico (DCIT) is known as Dehydrocholic Acid in the US.

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday 17 November 2010

INI Swine Ban Wormer




In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for INI Swine Ban Wormer



Pyrantel

Pyrantel tartrate (a derivative of Pyrantel) is reported as an ingredient of INI Swine Ban Wormer in the following countries:


  • United States

International Drug Name Search

Saturday 13 November 2010

Calcipotriolo




Calcipotriolo may be available in the countries listed below.


Ingredient matches for Calcipotriolo



Calcipotriol

Calcipotriolo (DCIT) is also known as Calcipotriol (Rec.INN)

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday 10 November 2010

Eptavit




Eptavit may be available in the countries listed below.


Ingredient matches for Eptavit



Calcium Carbonate

Calcium Carbonate is reported as an ingredient of Eptavit in the following countries:


  • France

  • Luxembourg

Colecalciferol

Colecalciferol is reported as an ingredient of Eptavit in the following countries:


  • France

  • Luxembourg

International Drug Name Search

Tuesday 9 November 2010

Natrium Bicarbonicum Sintetica




Natrium Bicarbonicum Sintetica may be available in the countries listed below.


Ingredient matches for Natrium Bicarbonicum Sintetica



Sodium Bicarbonate

Sodium Bicarbonate is reported as an ingredient of Natrium Bicarbonicum Sintetica in the following countries:


  • Switzerland

International Drug Name Search

Friday 5 November 2010

Protriptyline Hydrochloride




Ingredient matches for Protriptyline Hydrochloride



Protriptyline

Protriptyline Hydrochloride (BANM, USAN) is known as Protriptyline in the US.

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday 4 November 2010

Invigen




Invigen may be available in the countries listed below.


Ingredient matches for Invigen



Gentamicin

Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Invigen in the following countries:


  • Bangladesh

International Drug Name Search

Tuesday 2 November 2010

Epitril




Epitril may be available in the countries listed below.


Ingredient matches for Epitril



Clonazepam

Clonazepam is reported as an ingredient of Epitril in the following countries:


  • India

International Drug Name Search

Bat Zeta




Bat Zeta may be available in the countries listed below.


Ingredient matches for Bat Zeta



Cetylpyridinium

Cetylpyridinium chloride (a derivative of Cetylpyridinium) is reported as an ingredient of Bat Zeta in the following countries:


  • Italy

International Drug Name Search

Friday 22 October 2010

Parutox




Parutox may be available in the countries listed below.


Ingredient matches for Parutox



Pantothenate

Pantethine is reported as an ingredient of Parutox in the following countries:


  • Japan

International Drug Name Search

Tuesday 19 October 2010

Norotyl




Norotyl may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Norotyl



Tylosin

Tylosin is reported as an ingredient of Norotyl in the following countries:


  • Australia

  • New Zealand

  • South Africa

  • United Kingdom

International Drug Name Search

Monday 18 October 2010

Gentamicina Ranbaxy




Gentamicina Ranbaxy may be available in the countries listed below.


Ingredient matches for Gentamicina Ranbaxy



Gentamicin

Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Gentamicina Ranbaxy in the following countries:


  • Italy

International Drug Name Search

D-Histaplus




D-Histaplus may be available in the countries listed below.


Ingredient matches for D-Histaplus



Desloratadine

Desloratadine is reported as an ingredient of D-Histaplus in the following countries:


  • Chile

International Drug Name Search

Saturday 16 October 2010

Sandrena




In the US, Sandrena is a member of the drug class estrogens and is used to treat Atrophic Urethritis, Atrophic Vaginitis, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian Failure and Prostate Cancer.

UK matches:

  • Sandrena 0.5 mg gel (SPC)
  • Sandrena 1.0 mg gel (SPC)

Ingredient matches for Sandrena



Estradiol

Estradiol is reported as an ingredient of Sandrena in the following countries:


  • Australia

  • Chile

  • Mexico

Estradiol hemihydrate (a derivative of Estradiol) is reported as an ingredient of Sandrena in the following countries:


  • Brazil

  • Italy

  • Switzerland

  • United Kingdom

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday 15 October 2010

Korylan




Korylan may be available in the countries listed below.


Ingredient matches for Korylan



Codeine

Codeine phosphate hemihydrate (a derivative of Codeine) is reported as an ingredient of Korylan in the following countries:


  • Slovakia

Paracetamol

Paracetamol is reported as an ingredient of Korylan in the following countries:


  • Slovakia

International Drug Name Search

Zolagel




Zolagel may be available in the countries listed below.


Ingredient matches for Zolagel



Miconazole

Miconazole nitrate (a derivative of Miconazole) is reported as an ingredient of Zolagel in the following countries:


  • Indonesia

International Drug Name Search

Wednesday 13 October 2010

Nasentropfen K Hexal




Nasentropfen K Hexal may be available in the countries listed below.


Ingredient matches for Nasentropfen K Hexal



Xylometazoline

Xylometazoline hydrochloride (a derivative of Xylometazoline) is reported as an ingredient of Nasentropfen K Hexal in the following countries:


  • Germany

  • Luxembourg

International Drug Name Search

Saturday 9 October 2010

Coranzoll




Coranzoll may be available in the countries listed below.


Ingredient matches for Coranzoll



Miconazole

Miconazole is reported as an ingredient of Coranzoll in the following countries:


  • Japan

International Drug Name Search

Monday 4 October 2010

Oxacillina




Oxacillina may be available in the countries listed below.


Ingredient matches for Oxacillina



Oxacillin

Oxacillina (DCIT) is known as Oxacillin in the US.

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday 3 October 2010

Ci-son's




Ci-son's may be available in the countries listed below.


Ingredient matches for Ci-son's



Ciprofloxacin

Ciprofloxacin hydrochloride (a derivative of Ciprofloxacin) is reported as an ingredient of Ci-son's in the following countries:


  • Mexico

International Drug Name Search

Saturday 25 September 2010

Diclofenac-Retard




Diclofenac-Retard may be available in the countries listed below.


Ingredient matches for Diclofenac-Retard



Diclofenac

Diclofenac is reported as an ingredient of Diclofenac-Retard in the following countries:


  • Serbia

International Drug Name Search

Tuesday 21 September 2010

Invirase




In the US, Invirase (saquinavir systemic) is a member of the drug class protease inhibitors and is used to treat HIV Infection and Nonoccupational Exposure.

US matches:

  • Invirase

UK matches:

  • Invirase 200 mg hard capsules and 500 mg film-coated tablets (SPC)

Ingredient matches for Invirase



Saquinavir

Saquinavir is reported as an ingredient of Invirase in the following countries:


  • Bulgaria

  • Ireland

  • Peru

Saquinavir mesilate (a derivative of Saquinavir) is reported as an ingredient of Invirase in the following countries:


  • Australia

  • Austria

  • Bahrain

  • Belgium

  • Botswana

  • Brazil

  • Cambodia

  • Canada

  • Chile

  • Colombia

  • Croatia (Hrvatska)

  • Czech Republic

  • Denmark

  • Ecuador

  • Finland

  • France

  • Germany

  • Ghana

  • Greece

  • Hong Kong

  • Hungary

  • Iceland

  • Israel

  • Italy

  • Japan

  • Kenya

  • Laos

  • Luxembourg

  • Malawi

  • Malaysia

  • Mauritius

  • Mexico

  • Namibia

  • Netherlands

  • New Zealand

  • Nigeria

  • Norway

  • Oman

  • Philippines

  • Poland

  • Portugal

  • Romania

  • Russian Federation

  • Saudi Arabia

  • Serbia

  • Slovakia

  • Spain

  • Sudan

  • Sweden

  • Switzerland

  • Tanzania

  • Uganda

  • United Kingdom

  • United States

  • Uruguay

  • Venezuela

  • Vietnam

  • Zambia

  • Zimbabwe

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday 19 September 2010

Neo Sampoon




Neo Sampoon may be available in the countries listed below.


Ingredient matches for Neo Sampoon



Menfegol

Menfegol is reported as an ingredient of Neo Sampoon in the following countries:


  • Hong Kong

  • Singapore

International Drug Name Search

Topiramato Milo




Topiramato Milo may be available in the countries listed below.


Ingredient matches for Topiramato Milo



Topiramate

Topiramate is reported as an ingredient of Topiramato Milo in the following countries:


  • Spain

International Drug Name Search

Saturday 18 September 2010

Novirax




Novirax may be available in the countries listed below.


Ingredient matches for Novirax



Acyclovir

Aciclovir is reported as an ingredient of Novirax in the following countries:


  • Bangladesh

  • Oman

International Drug Name Search

Wednesday 15 September 2010

Progesterona L.CH.




Progesterona L.CH. may be available in the countries listed below.


Ingredient matches for Progesterona L.CH.



Progesterone

Progesterone is reported as an ingredient of Progesterona L.CH. in the following countries:


  • Chile

International Drug Name Search

Sunday 12 September 2010

Pronoctan




Pronoctan may be available in the countries listed below.


Ingredient matches for Pronoctan



Lormetazepam

Lormetazepam is reported as an ingredient of Pronoctan in the following countries:


  • Denmark

International Drug Name Search

Saturday 11 September 2010

Ethionamide




In the US, Ethionamide (ethionamide systemic) is a member of the drug class nicotinic acid derivatives and is used to treat Tuberculosis, Active.

US matches:

  • Ethionamide

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

J04AD03

CAS registry number (Chemical Abstracts Service)

0000536-33-4

Chemical Formula

C8-H10-N2-S

Molecular Weight

166

Therapeutic Category

Antitubercular agent

Chemical Name

4-Pyridinecarbothioamide, 2-ethyl-

Foreign Names

  • Ethionamidum (Latin)
  • Ethionamid (German)
  • Ethionamide (French)
  • Etionamida (Spanish)

Generic Names

  • Ethionamide (OS: USAN, BAN)
  • Éthionamide (OS: DCF)
  • Etionamide (OS: DCIT)
  • Aethionamidum (IS)
  • Bayer 5312 (IS: Bayer)
  • Etionizina (IS)
  • ETP (IS)
  • TH 1314 (IS)
  • Ethionamid (PH: Ph. Eur. 6)
  • Ethionamide (PH: BP 2010, Ph. Eur. 6, Ph. Int. 4, USP 32, JP XV)
  • Ethionamidum (PH: Ph. Int. 4, Ph. Eur. 6)

Brand Names

  • Ethatyl
    Aventis, South Africa


  • Ethide
    Lupin, India


  • Ethomid
    Macleods, Georgia


  • Etionamida
    Bestpharma, Chile


  • Eton
    Umeda, Thailand


  • Etyomid
    Koçak, Turkey


  • Trecator
    Wyeth, United States


  • Tubermin
    Meiji Seika Kaisha, Japan

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Nematox




Nematox may be available in the countries listed below.


Ingredient matches for Nematox



Albendazole

Albendazole is reported as an ingredient of Nematox in the following countries:


  • Bangladesh

International Drug Name Search

Angiozem




Angiozem may be available in the countries listed below.


Ingredient matches for Angiozem



Diltiazem

Diltiazem hydrochloride (a derivative of Diltiazem) is reported as an ingredient of Angiozem in the following countries:


  • Philippines

International Drug Name Search

Wednesday 8 September 2010

Betamethasone Ointment Augmented





Dosage Form: ointment, augmented
Betamethasone Dipropionate Ointment

(Augmented*) USP, 0.05%

(Potency expressed as betamethasone)


*Vehicle augments the penetration of the steroid


For Dermatologic Use Only - Not for Ophthalmic Use


Rx only



Betamethasone Ointment Augmented Description


Betamethasone Dipropionate Ointment (Augmented) USP, 0.05% contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticoid activity. Betamethasone dipropionate is the 17, 21-dipropionate ester of betamethasone.


Chemically, betamethasone dipropionate is 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, with the empirical formula C28H37FO7, a molecular weight of 504.6 and the following structural formula:



Betamethasone dipropionate is a white to creamy white, odorless powder insoluble in water; freely soluble in acetone and in chloroform; sparingly soluble in alcohol.


Each gram of Betamethasone Dipropionate Ointment (Augmented) USP, 0.05% contains: 0.643 mg betamethasone dipropionate, USP (equivalent to 0.5 mg betamethasone) in an optimized vehicle of propylene glycol, USP; propylene glycol stearate; white wax, NF; and white petrolatum, USP.



Betamethasone Ointment Augmented - Clinical Pharmacology


The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects.


Topical corticosteroids, such as betamethasone dipropionate, are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, antipruritic, and vasoconstrictive actions. However, while the physiologic, pharmacologic, and clinical effects of the corticosteroids are well known, the exact mechanisms of their actions in each disease are uncertain. Betamethasone dipropionate, a corticosteroid, has been shown to have topical (dermatologic) and systemic pharmacologic and metabolic effects characteristic of this class of drugs.



Pharmacokinetics


The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. (see DOSAGE AND ADMINISTRATION.)


Topical corticosteroids can be absorbed through normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. (see DOSAGE AND ADMINISTRATION.)


Once absorbed through the skin, topical corticosteroids enter pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees, are metabolized primarily in the liver and excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.


Studies performed with Betamethasone Dipropionate Ointment (Augmented) indicate that it is in the super-high range of potency as compared with other topical corticosteroids.



Indications and Usage for Betamethasone Ointment Augmented


Betamethasone Dipropionate Ointment (Augmented) USP, 0.05% is a super-high potency corticosteroid indicated for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years and older. The total dose should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis.



Contraindications


Betamethasone Dipropionate Ointment (Augmented) USP, 0.05% is contraindicated in patients who are hypersensitive to betamethasone dipropionate, to other corticosteroids, or to any ingredient in this preparation.



Precautions



General


Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients. Conditions which augment systemic absorption include the application of the more potent corticosteroids, use over large surface areas, prolonged use and the addition of occlusive dressings. Use of more than one corticosteroid-containing product at the same time may increase total systemic glucocorticoid exposure. (See DOSAGE AND ADMINISTRATION.)


Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, reduce the frequency of application, or to substitute a less potent steroid.


Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Patients should not be treated with amounts of Betamethasone Dipropionate Ointment (Augmented) greater than 50 g per week because of the potential for the drug to suppress HPA axis. Patients receiving super-potent corticosteroids should not be treated for more than 2 weeks at a time and only small areas should be treated at any one time due to the increased risk of HPA suppression.


At 14 g per day Betamethasone Dipropionate Ointment (Augmented) was shown to depress the plasma levels of adrenal cortical hormones following repeated application to diseased skin in patients with psoriasis. These effects were reversible upon discontinuation of treatment. At 7 g per day Betamethasone Dipropionate Ointment (Augmented) was shown to cause minimal inhibition of the HPA axis when applied 2 times daily for 2 to 3 weeks in healthy patients and in patients with psoriasis and eczematous disorders.


With 6 to 7 g of Betamethasone Dipropionate Ointment (Augmented) applied once daily for 3 weeks, no significant inhibition of the HPA axis was observed in patients with psoriasis and atopic dermatitis, as measured by plasma cortisol and 24-hour urinary 17-hydroxy-corticosteroid levels. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.


Pediatric patients may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity. (see PRECAUTIONS- Pediatric Use.)


If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted.


In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled. Betamethasone Dipropionate Ointment (Augmented) should not be used in the treatment of rosacea or perioral dermatitis, and it should not be used on the face, groin, or in the axillae.



Information for Patients


Patients using topical corticosteroids should receive the following information and instructions. This information is intended to aid in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects.


  1. This medication is to be used as directed by the physician and should not be used longer than the prescribed time period. It is for external use only. Avoid contact with the eyes.

  2. This medication should not be used for any disorder other than that for which it was prescribed.

  3. The treated skin area should not be bandaged, otherwise covered or wrapped, so as to be occlusive. (see DOSAGE AND ADMINISTRATION.)

  4. Patients should report to their physycian any signs of local adverse reactions.

  5. Patients should be advised not to use Betamethasone Dipropionate Ointment (Augmented) in the treatment of diaper dermatitis. Betamethasone Dipropionate Ointment (Augmented) should not be applied in the diaper areas as diapers or plastic pants may constitute occlusive dressing (see DOSAGE AND ADMINISTRATION).

  6. This medication should not be used on the face, underarms, or groin areas unless directed by the physician.

  7. As with other corticosteroids, therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, contact the physician.

  8. Other corticosteroid-containing products should not be used with Betamethasone Dipropionate Ointment (Augmented).


Laboratory Tests


The following tests may be helpful in evaluating HPA axis suppression:


 

ACTH stimulation test

 

Urinary free cortisol test


Carcinogenesis, Mutagenesis, and Impairment of Fertility


Long-term animal studies have not been performed to evaluate the carcinogenic potential of betamethasone dipropionate. Betamethasone was negative in the bacterial mutagenicity assay (Salmonella typhimurium and Escherichia coli), and in the mammalian cell mutagenicity assay (CHO/HGPRT). It was positive in the in-vitro, human lymphocyte chromosome aberration assay, and equivocal in the in-vivo mouse bone marrow micronucleus assay. This pattern of response is similar to that of dexamethasone and hydrocortisone. Studies in rabbits, mice and rats using intramuscular doses up to 1, 33 and 2 mg/kg, respectively, resulted in dose related increases in fetal resorptions in rabbits and mice.



Pregnancy


Teratogenic effects

Pregnancy category C


Corticosteroids have been shown to be teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Some corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. Betamethasone dipropionate has been shown to be teratogenic in rabbits when given by the intramuscular route at doses of 0.05 mg/kg. This dose is approximately 0.2 times the human topical dose of Betamethasone Dipropionate Ointment (Augmented) in mg/m2 of body surface area, assuming 100% absorption and the use in a 60 kg person of 7 g per day. The abnormalities observed included umbilical hernias, cephalocele and cleft palate. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Betamethasone Dipropionate Ointment (Augmented) should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.



Nursing Mothers


Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Betamethasone Dipropionate Ointment (Augmented) is administered to a nursing woman.



Pediatric Use


Use of Betamethasone Dipropionate Ointment (Augmented) in pediatric patients 12 years of age and younger is not recommended. (See CLINICAL PHARMACOLOGY and ADVERSE REACTIONS.)


Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.


Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels and an absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema. Chronic corticosteroid therapy may interfere with the growth and development of children.



Geriatric Use


Clinical studies of Betamethasone Dipropionate Ointment (Augmented) included 225 subjects who were 65 years of age and over and 46 subjects who were 75 years of age and over. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients. However, greater sensitivity of some older individuals cannot be ruled out.



Adverse Reactions


The local adverse reactions were reported with Betamethasone Dipropionate Ointment (Augmented) during controlled clinical trials were as follows: erythema, folliculitis, pruritus and vesiculation each occurring in less than 1% of patients.


The following additional local adverse reactions have been reported with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids. These reactions are listed in an approximately decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, and miliaria.


Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.



Overdosage


Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects. (see PRECAUTIONS.)



Betamethasone Ointment Augmented Dosage and Administration


Apply a thin film of Betamethasone Dipropionate Ointment (Augmented) USP, 0.05% to the affected skin once or twice daily. Betamethasone Dipropionate Ointment (Augmented) is a super-high potency topical corticosteroid. Treatment with Betamethasone Dipropionate Ointment (Augmented) should be limited to 50 g per week.


As with other corticosteroids, therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary.


Betamethasone Dipropionate Ointment (Augmented) should not be used with occlusive dressings. Betamethasone Dipropionate Ointment (Augmented) should not be applied to the diaper area if the patient requires diapers or plastic pants as these garments may constitute occlusive dressing.



How is Betamethasone Ointment Augmented Supplied


Betamethasone Dipropionate Ointment (Augmented) USP, 0.05% is supplied in 15 g (NDC 51642-1317-1) and 50 g (NDC 51672-1317-3) tubes; boxes of one; and in a 5 g physician sample (tube only).



Store at 20° - 25°C (68° - 77°F) [see USP Controlled Room Temperature].



Mfd. by: Taro Pharmaceuticals Inc., Brampton, Ontario, Canada L6T 1C1


Revised: September, 2006


LPK-4528-1

265



PRINCIPAL DISPLAY PANEL - 50 g Carton


NDC 51672-1317-3


50 g


Betamethasone Dipropionate

Ointment (Augmented*) USP, 0.05%


(Potency expressed as betamethasone)

*Vehicle augments the penetration of the steroid.


FOR DERMATOLOGIC USE ONLY.

NOT FOR OPHTHALMIC USE.


Rx only


TARO


Keep this and all medications out of the reach of children.










BETAMETHASONE DIPROPIONATE 
betamethasone dipropionate  ointment, augmented










Product Information
Product TypeHUMAN PRESCRIPTION DRUGNDC Product Code (Source)51672-1317
Route of AdministrationTOPICALDEA Schedule    








Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Betamethasone Dipropionate (Betamethasone)Betamethasone0.5 mg  in 1 g












Inactive Ingredients
Ingredient NameStrength
propylene glycol 
propylene glycol stearate 
petrolatum 
white wax 


















Product Characteristics
Color    Score    
ShapeSize
FlavorImprint Code
Contains      


























Packaging
#NDCPackage DescriptionMultilevel Packaging
151672-1317-55 g In 1 TUBENone
251672-1317-11 TUBE In 1 CARTONcontains a TUBE
215 g In 1 TUBEThis package is contained within the CARTON (51672-1317-1)
351672-1317-31 TUBE In 1 CARTONcontains a TUBE
350 g In 1 TUBEThis package is contained within the CARTON (51672-1317-3)










Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
ANDAANDA07675310/12/2004


Labeler - Taro Pharmaceuticals U.S.A., Inc. (145186370)









Establishment
NameAddressID/FEIOperations
Taro Pharmaceuticals Inc.206263295MANUFACTURE
Revised: 11/2011Taro Pharmaceuticals U.S.A., Inc.

Acix




Acix may be available in the countries listed below.


Ingredient matches for Acix



Acyclovir

Aciclovir is reported as an ingredient of Acix in the following countries:


  • Poland

Aluminium Hydroxide

Aluminium Hydroxide hydrate (Algeldrate) (a derivative of Aluminium Hydroxide) is reported as an ingredient of Acix in the following countries:


  • Czech Republic

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Tuesday 7 September 2010

Zantac




In some countries, this medicine may only be approved for veterinary use.


In the US, Zantac (ranitidine systemic) is a member of the drug class H2 antagonists and is used to treat Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Erosive Esophagitis, Gastric Ulcer Maintenance Treatment, Gastrointestinal Hemorrhage, GERD, Indigestion, Pathological Hypersecretory Conditions, Stomach Ulcer, Stress Ulcer Prophylaxis, Surgical Prophylaxis and Zollinger-Ellison Syndrome.

US matches:

  • Zantac

  • Zantac 150 EFFERdose Effervescent Tablets

  • Zantac 25 mg EFFERdose Effervescent Tablets

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  • Zantac 300

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  • Zantac Cool Mint

UK matches:

  • Zantac 75 Relief (SPC)
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  • Zantac Effervescent Tablets 150mg (GlaxoSmithKline UK) (SPC)
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  • Zantac Injection 50mg/2ml (GlaxoSmithKline UK) (SPC)
  • Zantac Syrup (GlaxoSmithKline UK) (SPC)
  • Zantac Tablets 150mg (GlaxoSmithKline UK) (SPC)
  • Zantac Tablets 300mg (GlaxoSmithKline UK) (SPC)

Ingredient matches for Zantac



Ranitidine

Ranitidine is reported as an ingredient of Zantac in the following countries:


  • Argentina

  • Bahrain

  • Bulgaria

  • Cyprus

  • Ethiopia

  • Iran

  • Israel

  • Jordan

  • Kuwait

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  • Luxembourg

  • Peru

  • Qatar

  • Romania

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  • Taiwan

  • Tunisia

  • United Arab Emirates

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  • Yemen

Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Zantac in the following countries:


  • Antigua & Barbuda

  • Argentina

  • Aruba

  • Australia

  • Austria

  • Bahamas

  • Bangladesh

  • Barbados

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  • Malaysia

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  • Nicaragua

  • Norway

  • Oman

  • Panama

  • Peru

  • Philippines

  • Poland

  • Portugal

  • Romania

  • Russian Federation

  • Saint Lucia

  • Singapore

  • Slovakia

  • South Africa

  • Spain

  • Sri Lanka

  • Sweden

  • Thailand

  • Trinidad & Tobago

  • Turkey

  • United Kingdom

  • United States

  • Venezuela

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday 1 September 2010

Nutropin




In the US, Nutropin (somatropin systemic) is a member of the drug class growth hormones and is used to treat Adult Human Growth Hormone Deficiency, Growth Retardation - Chronic Renal Failure, Hypopituitarism, Idiopathic Short Stature, Pediatric Growth Hormone Deficiency, Short Stature for Age and Turner's Syndrome.

US matches:

  • Nutropin

  • Nutropin AQ

  • Nutropin AQ NuSpin

  • Nutropin AQ Pen

  • Nutropin AQ Vials

  • Nutropin AQ NuSpin 10

  • Nutropin AQ NuSpin 5

  • Nutropin Aq Subcutaneous, Injection

  • Nutropin Subcutaneous, Injection

  • Nutropin Depot

Ingredient matches for Nutropin



Somatropine

Somatropine is reported as an ingredient of Nutropin in the following countries:


  • Canada

  • Greece

  • Hungary

  • Luxembourg

  • Portugal

  • United States

International Drug Name Search

Ramipril HCT Actavis




Ramipril/HCT Actavis may be available in the countries listed below.


Ingredient matches for Ramipril/HCT Actavis



Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Ramipril/HCT Actavis in the following countries:


  • Austria

  • Switzerland

Ramipril

Ramipril is reported as an ingredient of Ramipril/HCT Actavis in the following countries:


  • Austria

  • Switzerland

International Drug Name Search

Wednesday 25 August 2010

Narcan




In some countries, this medicine may only be approved for veterinary use.


In the US, Narcan (naloxone systemic) is a member of the drug class antidotes and is used to treat Opioid Overdose.

US matches:

  • Narcan

Ingredient matches for Narcan



Naloxone

Naloxone hydrochloride (a derivative of Naloxone) is reported as an ingredient of Narcan in the following countries:


  • Brazil

  • France

  • Greece

  • Ireland

  • Italy

  • Luxembourg

  • New Zealand

  • Oman

  • Portugal

  • Taiwan

  • Thailand

  • United Kingdom

  • United States

International Drug Name Search

Sunday 22 August 2010

Betahistin AL




Betahistin AL may be available in the countries listed below.


Ingredient matches for Betahistin AL



Betahistine

Betahistine dimesilate (a derivative of Betahistine) is reported as an ingredient of Betahistin AL in the following countries:


  • Germany

International Drug Name Search

Pharex Ciprofloxacin




Pharex Ciprofloxacin may be available in the countries listed below.


Ingredient matches for Pharex Ciprofloxacin



Ciprofloxacin

Ciprofloxacin hydrochloride (a derivative of Ciprofloxacin) is reported as an ingredient of Pharex Ciprofloxacin in the following countries:


  • Philippines

International Drug Name Search

Friday 20 August 2010

Taxocef




Taxocef may be available in the countries listed below.


Ingredient matches for Taxocef



Cefotaxime

Cefotaxime sodium salt (a derivative of Cefotaxime) is reported as an ingredient of Taxocef in the following countries:


  • Turkey

International Drug Name Search

Friday 13 August 2010

Sultrian




Sultrian may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Sultrian



Sulfamethoxazole

Sulfamethoxazole is reported as an ingredient of Sultrian in the following countries:


  • France

Trimethoprim

Trimethoprim is reported as an ingredient of Sultrian in the following countries:


  • France

International Drug Name Search

Hyopan




Hyopan may be available in the countries listed below.


Ingredient matches for Hyopan



Scopolamine

Scopolamine butylbromide (a derivative of Scopolamine) is reported as an ingredient of Hyopan in the following countries:


  • Bahrain

  • Ethiopia

  • Oman

International Drug Name Search

Wednesday 11 August 2010

Uro Cefasabal NF




Uro Cefasabal NF may be available in the countries listed below.


Ingredient matches for Uro Cefasabal NF



Pipemidic Acid

Pipemidic Acid is reported as an ingredient of Uro Cefasabal NF in the following countries:


  • Peru

International Drug Name Search

Friday 6 August 2010

Priconazole




In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Priconazole



Miconazole

Miconazole nitrate (a derivative of Miconazole) is reported as an ingredient of Priconazole in the following countries:


  • United States

International Drug Name Search

Tuesday 27 July 2010

Neosynephrin-POS




Neosynephrin-POS may be available in the countries listed below.


Ingredient matches for Neosynephrin-POS



Phenylephrine

Phenylephrine hydrochloride (a derivative of Phenylephrine) is reported as an ingredient of Neosynephrin-POS in the following countries:


  • Czech Republic

  • Germany

  • Poland

International Drug Name Search

Saturday 24 July 2010

Normovite




Normovite may be available in the countries listed below.


Ingredient matches for Normovite



Ferrous Glucoheptonate

Ferrous Glucoheptonate is reported as an ingredient of Normovite in the following countries:


  • Spain

Folic Acid

Folic Acid is reported as an ingredient of Normovite in the following countries:


  • Spain

International Drug Name Search

Friday 23 July 2010

Nipolept




Nipolept may be available in the countries listed below.


Ingredient matches for Nipolept



Zotepine

Zotepine is reported as an ingredient of Nipolept in the following countries:


  • Austria

  • Germany

International Drug Name Search

Sunday 18 July 2010

Rino naftazolina




Rino naftazolina may be available in the countries listed below.


Ingredient matches for Rino naftazolina



Naphazoline

Naphazoline hydrochloride (a derivative of Naphazoline) is reported as an ingredient of Rino naftazolina in the following countries:


  • Georgia

  • Italy

  • Malta

International Drug Name Search

Wednesday 14 July 2010

Asialum




Asialum may be available in the countries listed below.


Ingredient matches for Asialum



Aluminium Hydroxide

Aluminium Hydroxide is reported as an ingredient of Asialum in the following countries:


  • Thailand

Magnesium Hydroxide

Magnesium Hydroxide is reported as an ingredient of Asialum in the following countries:


  • Thailand

International Drug Name Search

Tuesday 13 July 2010

Sarinex




Sarinex may be available in the countries listed below.


Ingredient matches for Sarinex



Desloratadine

Desloratadine is reported as an ingredient of Sarinex in the following countries:


  • Bangladesh

International Drug Name Search

Monday 12 July 2010

Noprilam




Noprilam may be available in the countries listed below.


Ingredient matches for Noprilam



Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Noprilam in the following countries:


  • Malta

Clavulanate

Clavulanic Acid potassium (a derivative of Clavulanic Acid) is reported as an ingredient of Noprilam in the following countries:


  • Malta

International Drug Name Search

Sunday 11 July 2010

Amoxicilline Qualimed




Amoxicilline Qualimed may be available in the countries listed below.


Ingredient matches for Amoxicilline Qualimed



Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Amoxicilline Qualimed in the following countries:


  • France

International Drug Name Search

Antak




Antak may be available in the countries listed below.


Ingredient matches for Antak



Ranitidine

Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Antak in the following countries:


  • Brazil

International Drug Name Search

Saturday 10 July 2010

Corylap




Corylap may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Corylap



Sulfadimethoxine

Sulfadimethoxine sodium (a derivative of Sulfadimethoxine) is reported as an ingredient of Corylap in the following countries:


  • France

Trimethoprim

Trimethoprim is reported as an ingredient of Corylap in the following countries:


  • France

International Drug Name Search

Friday 9 July 2010

A-Acido




A-Acido may be available in the countries listed below.


Ingredient matches for A-Acido



Tretinoin

Tretinoin is reported as an ingredient of A-Acido in the following countries:


  • Argentina

International Drug Name Search

Sunday 4 July 2010

DCCK




DCCK may be available in the countries listed below.


Ingredient matches for DCCK



Dihydroergotoxine

Dihydroergotoxine mesilate (a derivative of Dihydroergotoxine) is reported as an ingredient of DCCK in the following countries:


  • Germany

  • Luxembourg

International Drug Name Search

Saturday 3 July 2010

Charcoal, Activated




In some countries, this medicine may only be approved for veterinary use.

Scheme

Ph. Eur.

ATC (Anatomical Therapeutic Chemical Classification)

A07BA

CAS registry number (Chemical Abstracts Service)

0016291-96-6

Therapeutic Categories

Antidote

Pharmaceutic aid

Antidiarrhoeal agent

Intestinal adsorbent

Foreign Names

  • Carbo activatus (Latin)
  • Kohle, medizinische (German)
  • Charbon active (French)
  • Carbone attivato (Spanish)

Generic Names

  • Medicinal Carbon (OS: JAN)
  • Adsorbierende Kohle (IS)
  • Aktivkohle (IS)
  • Carbo medicinalis (IS)
  • Charbon medicinal (IS)
  • Charcoal (IS)
  • E 153 (IS)
  • Holzkohle, gereinigte (IS)
  • Medicinal Carbon (IS)
  • Medizinische Kohle (IS)
  • Carbo activatus (PH: Ph. Int. 4, Ph. Eur. 6)
  • Charbon activé (PH: Ph. Eur. 6)
  • Charcoal, Activated (PH: BP 2010, Ph. Int. 4, USP 32, Ph. Eur. 6)
  • Medizinische Kohle (PH: Ph. Eur. 6)

Brand Names

  • Acticarbine (Charcoal, Activated and Papaverine)
    Elerté, France


  • Actidose
    Paddock, United States


  • Actidose-Aqua
    Cambridge Laboratories, United Kingdom; Paddock, United States


  • Actidose-Aqua (veterinary use)
    Cambridge Laboratories, United Kingdom


  • Activate Charcoal
    BHFZ, Georgia


  • Adsorba
    Gambro, United States


  • Aktivt kul Norit
    Norit, Denmark


  • Aktyvinta Anglis Sanitas
    Sanitas, Lithuania


  • Aktyvintoji Anglis
    Corpus Medica, Lithuania


  • Aqueous Charcodote
    Pharmascience, Singapore


  • Arkocaps Kohle
    Arko Diffusion, Switzerland


  • Arkocapsulas Carbon Veg
    Arkochim, Spain


  • Arkogélules Charbon Végétal
    Arkopharma, France


  • BCK (veterinary use)
    Fort Dodge, United Kingdom


  • Bekarbon
    Kimia Farma, Indonesia


  • Biocarbon
    Trenka, Austria; Trenka, Bahrain; Trenka, Malta


  • Carbactive
    Cooper, France


  • Carbargal
    Roemmers, Venezuela


  • Carbo activatus
    Briz, Latvia; Egis, Hungary


  • Carbo Medicinalis "Chepharin"
    Pannonpharma, Hungary


  • Carbo Medicinalis Sanova
    Sanova, Austria


  • Carbo medicinalis
    Abcur, Sweden


  • Carbo Medicinalis
    Fampharm, Serbia; ICN, Lithuania; ICN, Poland; ICN, Slovakia; Leiras, Finland


  • Carbocit (Charcoal, Activated and Bismuth Subgallate)
    Imuna, Slovakia


  • Carbomed
    Jadran, Croatia (Hrvatska)


  • Carbomix
    Beacon, United Kingdom; Excelsior, Taiwan; Leiras, Finland; Mayne, Ireland; Norit, Norway; Norit NV-NL, Italy; Solvay, Sweden; Tonipharm, France


  • Carbomix (veterinary use)
    Meadow Animals, United Kingdom


  • Carbon Belloc
    Spedrog-Caillon, Argentina


  • Carbon Eczane
    Eczane, Argentina


  • Carbon Medical
    H. Medica, Argentina


  • Carbon Oriental
    Oriental, Argentina


  • Carbon Ultra Adsor Lainco
    Lainco, Spain


  • Carbone Belloc
    Pasquali, Italy


  • Carbon-vegetal
    Fitomax, Peru


  • Carbophos
    Tradiphar, France


  • Carbo-Pulbit (Charcoal, Activated and Bismuth Subnitrate (veterinary use))
    Bayer Tiergesundheit, Austria


  • Carbosorb
    AFT, New Zealand; Imuna, Czech Republic; Imuna, Slovakia; Phebra, Australia


  • Carbosorb (Charcoal, Activated and Sorbitol)
    AFT, New Zealand


  • Carbosylane (Charcoal, Activated and Dimeticone)
    Lilly, Greece


  • Carbosylane (Charcoal, Activated and Simeticone)
    Grimberg, France


  • Carbosylane Enfant (Charcoal, Activated and Simeticone (pediatric))
    Grimberg, France


  • Carbotox
    Schwarz, Czech Republic


  • Carbotox (Charcoal, Activated andSodium Thiosulfate)
    Imuna, Slovakia


  • Charbon de belloc
    Medgenix, Belgium; Super Diet, France


  • CharcoAid
    Little Remedies, United States


  • Charcoal Camden
    Camden, Singapore


  • Charcoal
    Mason, United States; Red Seal, New Zealand


  • CharcoCaps
    W.F. Young, United States


  • Charcodote
    Genmedix, Israel; Pharmascience, Hong Kong; Pliva Pharma, United Kingdom


  • Charcotrace
    Phebra, Australia


  • Colocarb
    Expanpharm, France


  • EZ-Char
    Paddock, United States


  • Formocarbine
    GlaxoSmithKline, France


  • Insta-Char
    Kerr, United States


  • Kohle-Compretten
    Merck, Germany; Merck, Luxembourg; Merck, Norway


  • Kohle-Hevert
    Hevert, Germany


  • Kohle-Pulvis
    Köhler, Germany


  • Kohletabletten Hänseler
    Hänseler, Switzerland


  • Kohle-Tabletten
    Cheplapharm, Germany


  • Kolemed
    Rösch & Handel, Austria


  • Kolsuspension
    Abigo, Sweden; Cyntos, Switzerland


  • Kull
    Abigon, Norway


  • Linotar
    Trans Dermal, Australia


  • Liqui-Char
    Monarch, United States; Oxford, United Kingdom


  • Liqui-Char-Vet (veterinary use)
    Arnolds, United Kingdom


  • Mamograf
    Temis-Lostalo, Argentina


  • Medicinsko oglje
    Gorenjske, Slovenia


  • Medikol
    Solvay, Norway; Solvay, Sweden


  • Minicam
    Gramon, Argentina


  • Nature's Way Activated Charcoal
    Health and Herbs, New Zealand


  • Norit Carbomix
    Kela, Belgium; Norit, Austria


  • Norit
    Kela, Belgium; Kela, Luxembourg; Norit, Austria; Norit, Israel; Norit, Netherlands; Norit, Romania; Pharmasyn, Greece


  • Phytopharma Charbon
    Arko Diffusion, Switzerland


  • Topsharp (veterinary use)
    Hesse, Germany


  • Toxicarb
    SERB, France


  • Ultra Adsorb
    Lainco, Spain


  • Ultracarbon
    E. Merck, Ethiopia; Merck, Germany; Merck, Thailand; Merck Consumer Health, Singapore


  • Veterinair Norit (veterinary use)
    Norit vet, Netherlands

International Drug Name Search

Glossary

ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Ph. Eur.European Pharmacopoeia

Click for further information on drug naming conventions and International Nonproprietary Names.